Matthew Perry was 'angry' in final days due to testosterone shots, says pal
Matthew Perry 's autopsy report paints a grim picture of the final days of the actor's life.
The document revealed how a female friend had stated that he had become "angry and mean" in the weeks leading up to his death due to testosterone shots he had been taking. The report also detailed how Matthew had a lethal amount of ketamine in his body as well as buprenorphine which is used to ease pain and help with addiction to opioids.
He had also been taking Tamoxifen - a drug typically used to treat Breast Cancer - to help with weight loss, as well as nicotine lollipops and anti-diabetic medication. He was trying to quit smoking when he died with his live-in assistant claiming he had been smoking around two packs of cigarettes a day.
READ MORE Friends star Matthew Perry's cause of death confirmed as accident from 'acute effects of ketamine'
Matthew passed away from the effects of ketamine in his system (Los Angeles Times via Getty Images)
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The medical examiner’s report - obtained by the Mirror - detailed the extent of Matthew's reliance on both over the counter and prescription drugs to get by in life. It states: “In the assistant’s bedroom, there were multiple open, empty, half-filled medication bottles prescribed to the decedent, as well as over-the-counter medications, vitamins, digestive aids and dishes filled with multiple various loose pills, tablets, caplets, candy and breath mints.".
It also described how in Matthew's bathroom there were “prescribed ointments, digestive aids and oral rinses.” Matthew had been having ketamine infusion treatment regularly prior to passing away, however, the report claimed that the ketamine in his body had come from somewhere else and was not part of the treatments.
Ketamine has a half-life of just three to four hours and his last infusion had been a week and a half before his death. Dr. Bankole Johnson - a world renowned neuroscientist - told Page Six that “It is more likely this was recreational ketamine use.” They added: “It would be questionable medicine to provide ketamine to someone also using buprenorphine - a true recipe for disaster.”
Jennifer said she had been texting Matthew on the morning of October 28 (Archive Photos)
Matthew shared a picture of his hot tub just days before he died in it (Instagram)Matthew previously wrote about his dislike for ketamine in his 2022 memoir Friends, Lovers, and the Big Terrible Thing: A Memoir. He referred to treatments he received while he stayed at a Swiss rehab facility during the Covid-19 pandemic saying: “Taking K is like being hit in the head with a giant happy shovel. But the hangover was rough and outweighed the shovel. Ketamine was not for me.”
Matthew was not meant to be receiving further ketamine infusions according to his anaesthesiologist Dr. Ataoin who stated in the autopsy report that he didn't need them anymore as “his depression was fine.” Jennifer Aniston - Matthew's former Friends co-star and personal friend - recalled to Variety earlier this month how she had been texting Matthew on the day he died before he was found unresponsive in his hot tub.
She claimed that he was in a good place saying: “He had quit smoking. He was getting in shape. He was happy - that’s all I know. I was literally texting with him that morning, funny Matty. He was not in pain. He wasn’t struggling. He was happy.”
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