Just 18 months after their first-ever meeting, Manchester City and RB Leipzig are due to face off once more in the Champions League.
The two clubs met in the 2021-22 group stage, as Pep Guardiola's City looked to start again after losing the previous season's final against Chelsea. The Premier League team won their home game 6-3, despite Christopher Nkunku scoring a hat-trick for the visitors, while the Bundesliga outfit won 2-1 back in Germany with Kyle Walker picking up a red card.
City go into the game after losing top spot in the Premier League over the weekend, dropping points away to Nottingham Forest. Die Roten Bullen, meanwhile, are outside the Champions League places domestically after a slow start saw manager Domenico Tedesco replaced by Marco Rose.
City finished top of their group once more this season, having fallen at the hands of Real Madrid in last season's semi-finals. Guardiola's team remain unbeaten in this season's competition, winning four games and drawing two to finish ahead of Borussia Dortmund, Sevilla and FC Copenhagen.
Things were tougher for Leipzig, who lost their first two games against Shakhtar Donetsk and Real Madrid. They needed four wins in a row to make it through, doing a double over Celtic and putting four past Shakhtar in the winner-take-all final group game.
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Three of City's four league defeats this season have come on the road, potentially giving their opponents some hope for the first leg. However, Rose's team suffered defeat in their last league game at Red Bull Arena when Union Berlin came to town.
Who will win on Wednesday night? Have your say in the comments section
Manchester City finished with 10 men the last time they travelled to Leipzig (Getty Images)RB Leipzig's best Champions League run came in 2020, when they beat Tottenham and Atletico Madrid before falling to Paris Saint-Germain in the semi-finals. City, meanwhile, have two semi-final appearances as well as their run to the final in 2021.
Manchester City face RB Leipzig at Red Bull Arena on Wednesday 22 February.
Kick-off in Germany at 8pm.
As has been the case for a number of years, BT Sport will be the place for UK viewers to watch the Champions League, with RB Leipzig v Manchester City one of two live games on Wednesday. The Bundesliga v Premier League clash is being shown live on BT Sport 1 and BT Sport Ultimate.
Coverage begins at 7pm with subscribers able to watch the match via the BT Sport app on their phones, tablets and laptops. There will also be live radio coverage on talkSPORT and BBC Radio 5 Live.
RB Leipzig vs Man City odds from Betfred:
RB Leipzig - 16/5
Draw - 13/5
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Man City - 5/6
*odds subject to change
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